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Prenatal Dexamethasone, as Used in Preterm Labor, Worsens the Impact of Postnatal Chlorpyrifos Exposure on Serotonergic Pathways

This study explores how glucocorticoids sensitize the developing brain to the organophosphate pesticide, chlorpyrifos. Pregnant rats received a standard therapeutic dose (0.2 mg/kg) of dexamethasone on gestational days 17–19; pups were given subtoxic doses of chlorpyrifos on postnatal days 1–4, (1 m...

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書誌詳細
主要な著者: Slotkin, Theodore A., Card, Jennifer, Seidler, Frederic J.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891922/
https://ncbi.nlm.nih.gov/pubmed/24280657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2013.10.014
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