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Prenatal Dexamethasone, as Used in Preterm Labor, Worsens the Impact of Postnatal Chlorpyrifos Exposure on Serotonergic Pathways

This study explores how glucocorticoids sensitize the developing brain to the organophosphate pesticide, chlorpyrifos. Pregnant rats received a standard therapeutic dose (0.2 mg/kg) of dexamethasone on gestational days 17–19; pups were given subtoxic doses of chlorpyrifos on postnatal days 1–4, (1 m...

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Dades bibliogràfiques
Autors principals: Slotkin, Theodore A., Card, Jennifer, Seidler, Frederic J.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891922/
https://ncbi.nlm.nih.gov/pubmed/24280657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2013.10.014
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