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Ubiquitin-Specific Protease 5 Is Required for the Efficient Repair of DNA Double-Strand Breaks

During the DNA damage response (DDR), ubiquitination plays an important role in the recruitment and regulation of repair proteins. However, little is known about elimination of the ubiquitination signal after repair is completed. Here we show that the ubiquitin-specific protease 5 (USP5), a deubiqui...

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Detalhes bibliográficos
Main Authors: Nakajima, Satoshi, Lan, Li, Wei, Leizhen, Hsieh, Ching-Lung, Rapić-Otrin, Vesna, Yasui, Akira, Levine, Arthur S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891734/
https://ncbi.nlm.nih.gov/pubmed/24454762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084899
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