Coordinate H3K9 and DNA methylation silencing of ZNFs in toxicant-induced malignant transformation

Genome-wide disruption of the epigenetic code is a hallmark of malignancy that encompasses many distinct, highly interactive modifications. Delineating the aberrant epigenome produced during toxicant-mediated malignant transformation will help identify the underlying epigenetic drivers of environmen...

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Main Authors: Severson, Paul L, Tokar, Erik J, Vrba, Lukas, Waalkes, Michael P, Futscher, Bernard W
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891689/
https://ncbi.nlm.nih.gov/pubmed/23974009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25926
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