Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation

Epigenetic dysfunction is a known contributor in carcinogenesis, and is emerging as a mechanism involved in toxicant-induced malignant transformation for environmental carcinogens such as arsenicals or cadmium. In addition to aberrant DNA methylation of single genes, another manifestation of epigene...

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Bibliografiske detaljer
Main Authors: Severson, Paul L., Tokar, Erik J., Vrba, Lukas, Waalkes, Michael P., Futscher, Bernard W.
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499325/
https://ncbi.nlm.nih.gov/pubmed/22976526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.22163
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