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miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer
miRNAs are important regulators of gene expression that are frequently deregulated in cancer, with aberrant DNA methylation being an epigenetic mechanism involved in this process. We previously identified miRNA promoter regions active in normal mammary cell types and here we analyzed which of these...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3547033/ https://ncbi.nlm.nih.gov/pubmed/23342147 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054398 |
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