Role for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells

BACKGROUND: The microRNA-200 family participates in the maintenance of an epithelial phenotype and loss of its expression can result in epithelial to mesenchymal transition (EMT). Furthermore, the loss of expression of miR-200 family members is linked to an aggressive cancer phenotype. Regulation of...

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Détails bibliographiques
Auteurs principaux: Vrba, Lukas, Jensen, Taylor J., Garbe, James C., Heimark, Ronald L., Cress, Anne E., Dickinson, Sally, Stampfer, Martha R., Futscher, Bernard W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805718/
https://ncbi.nlm.nih.gov/pubmed/20084174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008697
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