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Distinctive patterns of DNA methylation associated with Parkinson disease: Identification of concordant epigenetic changes in brain and peripheral blood leukocytes

Parkinson disease (PD) is a multifactorial neurodegenerative disorder with high incidence in the elderly, where environmental and genetic factors are involved in etiology. In addition, epigenetic mechanisms, including deregulation of DNA methylation have been recently associated to PD. As accurate d...

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Detalhes bibliográficos
Main Authors: Masliah, Eliezer, Dumaop, Wilmar, Galasko, Douglas, Desplats, Paula
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891683/
https://ncbi.nlm.nih.gov/pubmed/23907097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.25865
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