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Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes

Tobacco smoke exposure dramatically alters DNA methylation in blood cells and may mediate smoking-associated complex diseases through effects on immune cell function. However, knowledge of smoking effects in specific leukocyte subtypes is limited. To better characterize smoking–associated methylatio...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Su, Dan, Wang, Xuting, Campbell, Michelle R., Porter, Devin K., Pittman, Gary S., Bennett, Brian D., Wan, Ma, Englert, Neal A., Crowl, Christopher L., Gimple, Ryan N., Adamski, Kelly N., Huang, Zhiqing, Murphy, Susan K., Bell, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5147832/
https://ncbi.nlm.nih.gov/pubmed/27935972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166486
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