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Insulin-Receptor Interactions in Adipose Tissue Cells: Direct Measurement and Properties

An assay system is described for measurement of specific binding of [(125)I]insulin to intact fat cells and membrane fractions from such cells. The binding is time- and temperature-dependent and saturable with respect to insulin; the bound insulin is displaced by native insulin but not by oxidized o...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteur principal: Cuatrecasas, Pedro
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1971
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389168/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5288373/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.6.1264
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