Direct demonstration that receptor crosslinking or aggregation is important in insulin action
Exposure of adipocytes to antibodies to the insulin receptor results in a blockade of (125)I-labeled insulin binding, stimulation of glucose oxidation, and many more insulin-like effects. Allowing for differences in purity, antireceptor antibody is equipotent with insulin on a molar basis. Both the...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1978
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/279910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.9.4209 |
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