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Direct demonstration that receptor crosslinking or aggregation is important in insulin action

Exposure of adipocytes to antibodies to the insulin receptor results in a blockade of (125)I-labeled insulin binding, stimulation of glucose oxidation, and many more insulin-like effects. Allowing for differences in purity, antireceptor antibody is equipotent with insulin on a molar basis. Both the...

詳細記述

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書誌詳細
主要な著者: Kahn, C. Ronald, Baird, Kathleen L., Jarrett, David B., Flier, Jeffrey S.
フォーマット: Artigo
言語:Inglês
出版事項: 1978
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC336081/
https://ncbi.nlm.nih.gov/pubmed/279910
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