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Direct demonstration that receptor crosslinking or aggregation is important in insulin action

Exposure of adipocytes to antibodies to the insulin receptor results in a blockade of (125)I-labeled insulin binding, stimulation of glucose oxidation, and many more insulin-like effects. Allowing for differences in purity, antireceptor antibody is equipotent with insulin on a molar basis. Both the...

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Detaylı Bibliyografya
Asıl Yazarlar: Kahn, C. Ronald, Baird, Kathleen L., Jarrett, David B., Flier, Jeffrey S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1978
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC336081/
https://ncbi.nlm.nih.gov/pubmed/279910
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