Direct demonstration that receptor crosslinking or aggregation is important in insulin action

Exposure of adipocytes to antibodies to the insulin receptor results in a blockade of (125)I-labeled insulin binding, stimulation of glucose oxidation, and many more insulin-like effects. Allowing for differences in purity, antireceptor antibody is equipotent with insulin on a molar basis. Both the...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Kahn, C. Ronald, Baird, Kathleen L., Jarrett, David B., Flier, Jeffrey S.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1978
Aiheet:	Biological Sciences: Biochemistry
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/279910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.9.4209
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