Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase.

Eitemau Tebyg

• Hypothesis: ceramide conditionally activates atypical protein kinases C, Raf-1 and KSR through binding to their cysteine-rich domains.
  gan: van Blitterswijk, W J
  Cyhoeddwyd: (1998)
• Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells
  gan: Huwiler, Andrea, et al.
  Cyhoeddwyd: (2000)
• Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists.
  gan: Huwiler, A, et al.
  Cyhoeddwyd: (1995)
• Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.
  gan: Wang, H G, et al.
  Cyhoeddwyd: (1996)
• Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase
  gan: Terai, Kenta, et al.
  Cyhoeddwyd: (2005)