Bcl-2 interacting protein, BAG-1, binds to and activates the kinase Raf-1.

The Bcl-2 protein blocks programmed cell death (apoptosis) through an unknown mechanism. Previously we identified a Bcl-2 interacting protein BAG-1 that enhances the anti-apoptotic effects of Bcl-2. Like BAG-1, the serine/threonine protein kinase Raf-1 also can functionally cooperate with Bcl-2 in s...

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Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Wang, H G, Takayama, S, Rapp, U R, Reed, J C
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38936/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7063
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