Genetic variants influencing circulating lipid levels and risk of coronary artery disease

OBJECTIVES: Genetic studies might provide new insights into the biological mechanisms underlying lipid metabolism and risk of CAD. We therefore conducted a genome-wide association study to identify novel genetic determinants of LDL-c, HDL-c and triglycerides. METHODS AND RESULTS: We combined genome-...

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Detalhes bibliográficos
Main Authors: Waterworth, Dawn M, Ricketts, Sally L, Song, Kijoung, Chen, Li, Zhao, Jing Hua, Ripatti, Samuli, Aulchenko, Yurii S, Zhang, Weihua, Yuan, Xin, Lim, Noha, Luan, Jian’an, Ashford, Sofie, Wheeler, Eleanor, Young, Elizabeth H, Hadley, David, Thompson, John R, Braund, Peter S, Johnson, Toby, Struchalin, Maksim, Surakka, Ida, Luben, Robert, Khaw, Kay-Tee, Rodwell, Sheila A, Loos, Ruth J F, Boekholdt, S. Matthijs, Inouye, Michael, Deloukas, Panagiotis, Elliott, Paul, Schlessinger, David, Sanna, Serena, Scuteri, Angelo, Jackson, Anne, Mohlke, Karen L, Tuomilehto, Jaako, Roberts, Robert, Stewart, Alexandre, Kesäniemi, Y Antero, Mahley, Robert W, Grundy, Scott M, Hofman, Albert, McArdle, Wendy, Cardon, Lon, Waeber, Gérard, Vollenweider, Peter, Chambers, John C, Boehnke, Michael, Abecasis, Gonçalo R, Salomaa, Veikko, Järvelin, Marjo-Riitta, Barroso, Inês, Epstein, Stephen E, Hakonarson, Hakon H, Rader, Daniel J, Reilly, Muredach P, Witteman, Jacqueline C M, Hall, Alistair S, Samani, Nilesh J, Strachan, David P, Barter, Philip, van Duijn, Cornelia M, Kooner, Jaspal S, Peltonen, Leena, Wareham, Nicholas J, McPherson, Ruth, Mooser, Vincent, Sandhu, Manjinder S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891568/
https://ncbi.nlm.nih.gov/pubmed/20864672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.201020
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