Genetic variants influencing circulating lipid levels and risk of coronary artery disease

OBJECTIVES: Genetic studies might provide new insights into the biological mechanisms underlying lipid metabolism and risk of CAD. We therefore conducted a genome-wide association study to identify novel genetic determinants of LDL-c, HDL-c and triglycerides. METHODS AND RESULTS: We combined genome-...

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Hlavní autoři: Waterworth, Dawn M, Ricketts, Sally L, Song, Kijoung, Chen, Li, Zhao, Jing Hua, Ripatti, Samuli, Aulchenko, Yurii S, Zhang, Weihua, Yuan, Xin, Lim, Noha, Luan, Jian’an, Ashford, Sofie, Wheeler, Eleanor, Young, Elizabeth H, Hadley, David, Thompson, John R, Braund, Peter S, Johnson, Toby, Struchalin, Maksim, Surakka, Ida, Luben, Robert, Khaw, Kay-Tee, Rodwell, Sheila A, Loos, Ruth J F, Boekholdt, S. Matthijs, Inouye, Michael, Deloukas, Panagiotis, Elliott, Paul, Schlessinger, David, Sanna, Serena, Scuteri, Angelo, Jackson, Anne, Mohlke, Karen L, Tuomilehto, Jaako, Roberts, Robert, Stewart, Alexandre, Kesäniemi, Y Antero, Mahley, Robert W, Grundy, Scott M, Hofman, Albert, McArdle, Wendy, Cardon, Lon, Waeber, Gérard, Vollenweider, Peter, Chambers, John C, Boehnke, Michael, Abecasis, Gonçalo R, Salomaa, Veikko, Järvelin, Marjo-Riitta, Barroso, Inês, Epstein, Stephen E, Hakonarson, Hakon H, Rader, Daniel J, Reilly, Muredach P, Witteman, Jacqueline C M, Hall, Alistair S, Samani, Nilesh J, Strachan, David P, Barter, Philip, van Duijn, Cornelia M, Kooner, Jaspal S, Peltonen, Leena, Wareham, Nicholas J, McPherson, Ruth, Mooser, Vincent, Sandhu, Manjinder S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891568/
https://ncbi.nlm.nih.gov/pubmed/20864672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.201020
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