FGF21 signalling pathway and metabolic traits – genetic association analysis

Fibroblast growth factor 21 (FGF21) is a novel master regulator of metabolic profile. The biological actions of FGF21 are elicited upon its klotho beta (KLB)-facilitated binding to FGF receptor 1 (FGFR1), FGFR2 and FGFR3. We hypothesised that common polymorphisms in the FGF21 signalling pathway may...

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Detalhes bibliográficos
Main Authors: Kaess, Bernhard M, Barnes, Timothy A, Stark, Klaus, Charchar, Fadi J, Waterworth, Dawn, Song, Kijoung, Wang, William Y S, Vollenweider, Peter, Waeber, Gerard, Mooser, Vincent, Zukowska-Szczechowska, Ewa, Samani, Nilesh J, Hengstenberg, Christian, Tomaszewski, Maciej
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988092/
https://ncbi.nlm.nih.gov/pubmed/20717167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2010.130
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