A common variant in low density lipoprotein receptor-related protein 6 gene (LRP6) is associated with LDL-cholesterol: Tomaszewski LRP6 gene and LDL-C

OBJECTIVE: A rare mutation in low density lipoprotein receptor-related protein 6 gene (LRP6) was identified as the primary molecular defect underlying monogenic form of coronary artery disease. We hypothesised that common variants in LRP6 could predispose subjects to elevated LDL-cholesterol (LDL-C)...

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Detalhes bibliográficos
Main Authors: Tomaszewski, Maciej, Charchar, Fadi J., Barnes, Timothy, Gawron-Kiszka, Magdalena, Sedkowska, Agnieszka, Podolecka, Ewa, Kowalczyk, Jacek, Rathbone, Wendy, Kalarus, Zbigniew, Grzeszczak, Wladyslaw, Goodall, Alison H., Samani, Nilesh J., Zukowska-Szczechowska, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814817/
https://ncbi.nlm.nih.gov/pubmed/19667113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.185355
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