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Clinical and Pharmacotherapeutic Relevance of the Double-Chain Domain of the Angiotensin II Type 1 Receptor Blocker Olmesartan

We previously reported that the angiotensin II type 1 (AT(1)) receptor blocker (ARB) olmesartan has two important interactions to evoke inverse agonism (IA). We refer to these interactions as the “double-chain domain (DCD).” Since the clinical pharmacotherapeutic relevance of olmesartan is still unc...

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Detalhes bibliográficos
Main Authors: Kiya, Yoshihiro, Miura, Shin-ichiro, Fujino, Masahiro, Imaizumi, Satoshi, Karnik, Sadashiva S., Saku, Keijiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891519/
https://ncbi.nlm.nih.gov/pubmed/20374187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10641960903254430
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