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Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

The voltage-gated Na channel isoform 1.5 (Na(V)1.5) is the pore forming α-subunit of the voltage-gated cardiac Na channel, which is responsible for the initiation and propagation of cardiac action potentials. Mutations in the SCN5A gene encoding Na(V)1.5 have been linked to changes in the Na current...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Herren, Anthony W., Bers, Donald M., Grandi, Eleonora
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891248/
https://ncbi.nlm.nih.gov/pubmed/23771687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00306.2013
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