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Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias
The voltage-gated Na channel isoform 1.5 (Na(V)1.5) is the pore forming α-subunit of the voltage-gated cardiac Na channel, which is responsible for the initiation and propagation of cardiac action potentials. Mutations in the SCN5A gene encoding Na(V)1.5 have been linked to changes in the Na current...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3891248/ https://ncbi.nlm.nih.gov/pubmed/23771687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00306.2013 |
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