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Post-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmias

The voltage-gated Na channel isoform 1.5 (Na(V)1.5) is the pore forming α-subunit of the voltage-gated cardiac Na channel, which is responsible for the initiation and propagation of cardiac action potentials. Mutations in the SCN5A gene encoding Na(V)1.5 have been linked to changes in the Na current...

詳細記述

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書誌詳細
主要な著者: Herren, Anthony W., Bers, Donald M., Grandi, Eleonora
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891248/
https://ncbi.nlm.nih.gov/pubmed/23771687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00306.2013
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