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CaMKII-dependent regulation of cardiac Na(+) homeostasis

Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, Na(V)1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias. Ca(2)(+)/calmodulin-dependent protein kinas...

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Hlavní autoři: Grandi, Eleonora, Herren, Anthony W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3948048/
https://ncbi.nlm.nih.gov/pubmed/24653702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00041
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