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Protein structural ensembles are revealed by redefining X-ray electron density noise

To increase the power of X-ray crystallography to determine not only the structures but also the motions of biomolecules, we developed methods to address two classic crystallographic problems: putting electron density maps on the absolute scale of e(−)/Å(3) and calculating the noise at every point i...

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Bibliografiske detaljer
Main Authors: Lang, P. Therese, Holton, James M., Fraser, James S., Alber, Tom
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890839/
https://ncbi.nlm.nih.gov/pubmed/24363322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1302823110
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