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Accessing protein conformational ensembles using room-temperature X-ray crystallography
Modern protein crystal structures are based nearly exclusively on X-ray data collected at cryogenic temperatures (generally 100 K). The cooling process is thought to introduce little bias in the functional interpretation of structural results, because cryogenic temperatures minimally perturb the ove...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3182744/ https://ncbi.nlm.nih.gov/pubmed/21918110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111325108 |
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