A stem cell-like gene expression signature associates with inferior outcomes and a distinct microRNA expression profile in adults with primary cytogenetically normal acute myeloid leukemia

Acute myeloid leukemia (AML) is hypothesized to be sustained by self-renewing leukemia stem cells (LSCs). Recently, gene expression signatures (GES) from functionally defined AML LSC populations were reported, and expression of a ‘core enriched’ (CE) GES, representing 44 genes activated in LCSs, con...

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Xehetasun bibliografikoak
Egile Nagusiak: Metzeler, KH, Maharry, K, Kohlschmidt, J, Volinia, S, Mrózek, K, Becker, H, Nicolet, D, Whitman, SP, Mendler, JH, Schwind, S, Eisfeld, A-K, Wu, Y-Z, Powell, BL, Carter, TH, Wetzler, M, Kolitz, JE, Baer, MR, Carroll, AJ, Stone, RM, Caligiuri, MA, Marcucci, G, Bloomfield, CD
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890747/
https://ncbi.nlm.nih.gov/pubmed/23765227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.181
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