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(13)C NMR Metabolomic Evaluation of Immediate and Delayed Mild Hypothermia in Cerebrocortical Slices After Oxygen-Glucose Deprivation
BACKGROUND: Mild brain hypothermia (32°C–34°C) after human neonatal asphyxia improves neurodevelopmental outcomes. Astrocytes but not neurons have pyruvate carboxylase (PC) and an acetate uptake transporter. (13)C NMR spectroscopy of rodent brain extracts after administering [1-(13)C]glucose and [1,...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3890426/ https://ncbi.nlm.nih.gov/pubmed/23748856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31829c2d90 |
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