(13)C NMR Metabolomic Evaluation of Immediate and Delayed Mild Hypothermia in Cerebrocortical Slices After Oxygen-Glucose Deprivation

BACKGROUND: Mild brain hypothermia (32°C–34°C) after human neonatal asphyxia improves neurodevelopmental outcomes. Astrocytes but not neurons have pyruvate carboxylase (PC) and an acetate uptake transporter. (13)C NMR spectroscopy of rodent brain extracts after administering [1-(13)C]glucose and [1,...

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Main Authors: Liu, Jia, Segal, Mark, Kelly, Mark J.S., Pelton, Jeffrey G., Kim, Myungwon, James, Thomas L., Litt, Lawrence
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890426/
https://ncbi.nlm.nih.gov/pubmed/23748856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e31829c2d90
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