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The Influence of Neighboring Base Pairs upon Base-Pair Substitution Mutation Rates
The 2-aminopurine-induced transition, A·T → G·C, was studied at particular sites in bacteriophage T4 as a function of the nearby base-pair composition of the DNA. Changing a base pair changed the transition rate at the adjacent base pair up to 23-fold, and at the next base pair by a lesser amount. D...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5279518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.773 |
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