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The Influence of Neighboring Base Pairs upon Base-Pair Substitution Mutation Rates

The 2-aminopurine-induced transition, A·T → G·C, was studied at particular sites in bacteriophage T4 as a function of the nearby base-pair composition of the DNA. Changing a base pair changed the transition rate at the adjacent base pair up to 23-fold, and at the next base pair by a lesser amount. D...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autor Principal: Koch, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1971
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389040/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5279518/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.773
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