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The Influence of Neighboring Base Pairs upon Base-Pair Substitution Mutation Rates
The 2-aminopurine-induced transition, A·T → G·C, was studied at particular sites in bacteriophage T4 as a function of the nearby base-pair composition of the DNA. Changing a base pair changed the transition rate at the adjacent base pair up to 23-fold, and at the next base pair by a lesser amount. D...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1971
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC389040/ https://ncbi.nlm.nih.gov/pubmed/5279518 |
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