INVOLVEMENT OF ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY IN INFLAMMATORY DEMYELINATION IN A MOUSE MODEL OF NEUROMYELITIS OPTICA

Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system that can cause paralysis and blindness. The pathogenesis of NMO involves binding of immunoglobulin G autoantibodies to aquaporin-4 (AQP4) on astrocytes, which is thought to cause complement-dependent cy...

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Detaylı Bibliyografya
Asıl Yazarlar: Ratelade, Julien, Asavapanumas, Nithi, Ritchie, Alanna M., Wemlinger, Scott, Bennett, Jeffrey L., Verkman, A. S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890328/
https://ncbi.nlm.nih.gov/pubmed/23995423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-013-1172-z
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