Development of a Paediatric Population-Based Model of the Pharmacokinetics of Rivaroxaban

BACKGROUND: Venous thromboembolism has been increasingly recognised as a clinical problem in the paediatric population. Guideline recommendations for antithrombotic therapy in paediatric patients are based mainly on extrapolation from adult clinical trial data, owing to the limited number of clinica...

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Main Authors: Willmann, Stefan, Becker, Corina, Burghaus, Rolf, Coboeken, Katrin, Edginton, Andrea, Lippert, Jörg, Siegmund, Hans-Ulrich, Thelen, Kirstin, Mück, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2013
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889826/
https://ncbi.nlm.nih.gov/pubmed/23912563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-013-0090-5
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