Simultaneous Detection of Major Drug Resistance Mutations in the Protease and Reverse Transcriptase Genes for HIV-1 Subtype C by Use of a Multiplex Allele-Specific Assay

High-throughput, sensitive, and cost-effective HIV drug resistance (HIVDR) detection assays are needed for large-scale monitoring of the emergence and transmission of HIVDR in resource-limited settings. Using suspension array technology, we have developed a multiplex allele-specific (MAS) assay that...

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Main Authors: Zhang, Guoqing, Cai, Fangping, Zhou, Zhiyong, DeVos, Joshua, Wagar, Nick, Diallo, Karidia, Zulu, Isaac, Wadonda-Kabondo, Nellie, Stringer, Jeffrey S. A., Weidle, Paul J., Ndongmo, Clement B., Sikazwe, Izukanji, Sarr, Abdoulaye, Kagoli, Matthew, Nkengasong, John, Gao, Feng, Yang, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889749/
https://ncbi.nlm.nih.gov/pubmed/23985909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01669-13
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