Simultaneous Detection of Major Drug Resistance Mutations of HIV-1 Subtype B Viruses from Dried Blood Spot Specimens by Multiplex Allele-Specific Assay

A multiplex allele-specific (MAS) assay has been developed for the detection of HIV-1 subtype C drug resistance mutations (DRMs). We have optimized the MAS assay to determine subtype B DRMs in dried blood spots (DBS) collected from patients on antiretroviral therapy. The new assay accurately detecte...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Zhang, Guoqing, Cai, Fangping, de Rivera, Ivette Lorenzana, Zhou, Zhiyong, Zhang, Jing, Nkengasong, John, Gao, Feng, Yang, Chunfu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702749/
https://ncbi.nlm.nih.gov/pubmed/26560533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.02833-15
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