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Inhibition of TGF-β1 Signaling Promotes Central Memory T Cell Differentiation
The present study affirmed that isolated CD8(+) T cells express mRNA and produce TGF-β following cognate peptide recognition. Blockage of endogenous TGF-β with either a TGF-β-blocking antibody or a small molecule inhibitor of TGF-βRI enhances the generation of CD62L(high)/CD44(high) central memory C...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889640/ https://ncbi.nlm.nih.gov/pubmed/23904158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300472 |
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