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Inhibition of TGF-β1 Signaling Promotes Central Memory T Cell Differentiation

The present study affirmed that isolated CD8(+) T cells express mRNA and produce TGF-β following cognate peptide recognition. Blockage of endogenous TGF-β with either a TGF-β-blocking antibody or a small molecule inhibitor of TGF-βRI enhances the generation of CD62L(high)/CD44(high) central memory C...

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Bibliografski detalji
Glavni autori: Takai, Shinji, Schlom, Jeffrey, Tucker, Joanne, Tsang, Kwong Y., Greiner, John W.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889640/
https://ncbi.nlm.nih.gov/pubmed/23904158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300472
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