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Essential Roles for Mycobacterium tuberculosis Rel beyond the Production of (p)ppGpp

In Mycobacterium tuberculosis, the stringent response to amino acid starvation is mediated by the M. tuberculosis Rel (Rel(Mtb)) enzyme, which transfers a pyrophosphate from ATP to GDP or GTP to synthesize ppGpp and pppGpp, respectively. (p)ppGpp then influences numerous metabolic processes. Rel(Mtb...

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Detalhes bibliográficos
Main Authors: Weiss, Leslie A., Stallings, Christina L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889611/
https://ncbi.nlm.nih.gov/pubmed/24123821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00759-13
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