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Essential Roles for Mycobacterium tuberculosis Rel beyond the Production of (p)ppGpp

In Mycobacterium tuberculosis, the stringent response to amino acid starvation is mediated by the M. tuberculosis Rel (Rel(Mtb)) enzyme, which transfers a pyrophosphate from ATP to GDP or GTP to synthesize ppGpp and pppGpp, respectively. (p)ppGpp then influences numerous metabolic processes. Rel(Mtb...

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Bibliografske podrobnosti
Main Authors: Weiss, Leslie A., Stallings, Christina L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889611/
https://ncbi.nlm.nih.gov/pubmed/24123821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00759-13
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