Histone H3K27 Trimethylation Inhibits H3 Binding and Function of SET1-Like H3K4 Methyltransferase Complexes

Trimethylated histone H3 lysine 4 (H3K4) and H3K27 generally mark transcriptionally active and repressive chromatins, respectively. In most cell types, these two modifications are mutually exclusive, and this segregation is crucial for the regulation of gene expression. However, how this anticorrela...

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Main Authors: Kim, Dae-Hwan, Tang, Zhanyun, Shimada, Miho, Fierz, Beat, Houck-Loomis, Brian, Bar-Dagen, Maya, Lee, Seunghee, Lee, Soo-Kyung, Muir, Tom W., Roeder, Robert G., Lee, Jae W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889540/
https://ncbi.nlm.nih.gov/pubmed/24126056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00601-13
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