Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases

Activating signal cointegrator-2 (ASC-2), a coactivator of multiple transcription factors that include retinoic acid receptor (RAR), associates with histone H3-K4 methyltranferases (H3K4MTs) MLL3 and MLL4 in mixed-lineage leukemia. Here, we show that mice expressing a SET domain mutant of MLL3 share...

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Autori principali: Lee, Seunghee, Lee, Dong-Kee, Dou, Yali, Lee, Jeongkyung, Lee, Bora, Kwak, Eunyee, Kong, Young-Yun, Lee, Soo-Kyung, Roeder, Robert G., Lee, Jae W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2006
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1622834/
https://ncbi.nlm.nih.gov/pubmed/17021013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607313103
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