Synergistic Antibiotic Combination Powders of Colistin and Rifampicin Provide High Aerosolization Efficiency and Moisture Protection

For many respiratory infections caused by multidrug-resistant Gram-negative bacteria, colistin is the only effective antibiotic despite its nephrotoxicity. A novel inhaled combination formulation of colistin with a synergistic antimicrobial component of rifampicin was prepared via co-spray drying, a...

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Библиографические подробности
Главные авторы: Zhou, Qi (Tony), Gengenbach, Thomas, Denman, John A., Yu, Heidi H., Li, Jian, Chan, Hak Kim
Формат: Artigo
Язык:Inglês
Опубликовано: Springer US 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889531/
https://ncbi.nlm.nih.gov/pubmed/24129586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-013-9537-8
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