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Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity

The establishment and maintenance of cell polarity is an essential property governing organismal homeostasis, and loss of polarity is a common feature of cancer cells. The ability of epithelial cells to establish apical-basal polarity depends on intracellular signals generated from polarity proteins...

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Bibliografiska uppgifter
Huvudupphovsmän: Lewandowski, Katherine T., Piwnica-Worms, Helen
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Company of Biologists 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889397/
https://ncbi.nlm.nih.gov/pubmed/24259665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.129148
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