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Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association

The Par-1 protein kinases are conserved from yeast to humans, where they function as key polarity determinants. The mammalian Par-1 family is comprised of 4 members (Par-1a, -b, -c, and -d). Previously, we demonstrated that atypical protein kinase C (aPKC) phosphorylates the Par-1 kinases on a conse...

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Bibliographische Detailangaben
Hauptverfasser: Watkins, Janis L., Lewandowski, Katherine T., Meek, Sarah E. M., Storz, Peter, Toker, Alex, Piwnica-Worms, Helen
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587537/
https://ncbi.nlm.nih.gov/pubmed/19011111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809661105
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