Loss of Par-1a/MARK3/C-TAK1 Kinase Leads to Reduced Adiposity, Resistance to Hepatic Steatosis, and Defective Gluconeogenesis

Par-1 is an evolutionarily conserved protein kinase required for polarity in worms, flies, frogs, and mammals. The mammalian Par-1 family consists of four members. Knockout studies of mice implicate Par-1b/MARK2/EMK in regulating fertility, immune homeostasis, learning, and memory as well as adiposi...

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Main Authors: Lennerz, Jochen K., Hurov, Jonathan B., White, Lynn S., Lewandowski, Katherine T., Prior, Julie L., Planer, G. James, Gereau, Robert W., Piwnica-Worms, David, Schmidt, Robert E., Piwnica-Worms, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953066/
https://ncbi.nlm.nih.gov/pubmed/20733003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01472-09
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