Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo

Obesity is a major factor central to the development of insulin resistance and type 2 diabetes. The identification and characterization of genes involved in regulation of adiposity, insulin sensitivity, and glucose uptake are key to the design and development of new drug therapies for this disease....

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Detalhes bibliográficos
Main Authors: Hurov, Jonathan B., Huang, Mei, White, Lynn S., Lennerz, Jochen, Choi, Cheol Soo, Cho, You-Ree, Kim, Hyo-Jeong, Prior, Julie L., Piwnica-Worms, David, Cantley, Lewis C., Kim, Jason K., Shulman, Gerald I., Piwnica-Worms, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838456/
https://ncbi.nlm.nih.gov/pubmed/17372192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701179104
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