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A reporter based single step assay for evaluation of inhibitors targeting HIV-1 Rev–RRE interaction

Human immunodeficiency virus regulatory protein Rev (regulator of viral expression) is translated from a monocistronic transcript produced early in the viral replication cycle. Rev binds to the cis-acting, highly structured viral RNA sequence Rev response element (RRE) and the Rev–RRE complex primar...

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Hlavní autoři: Raina, Sumeer, Chande, Ajit G., Baba, Masanori, Mukhopadhyaya, Robin
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer India 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889232/
https://ncbi.nlm.nih.gov/pubmed/24426316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13337-013-0166-8
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