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A reporter based single step assay for evaluation of inhibitors targeting HIV-1 Rev–RRE interaction
Human immunodeficiency virus regulatory protein Rev (regulator of viral expression) is translated from a monocistronic transcript produced early in the viral replication cycle. Rev binds to the cis-acting, highly structured viral RNA sequence Rev response element (RRE) and the Rev–RRE complex primar...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Springer India
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889232/ https://ncbi.nlm.nih.gov/pubmed/24426316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13337-013-0166-8 |
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