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Targeting IL-15 in large granular lymphocyte leukemia

IL-15 is a cytokine that stimulates the proliferation of NK and T cells. Previous studies have shown that IL-15 is critical to the induction of T-cell large granular lymphocyte (T-LGL) leukemia. A Phase I trial of a humanized antibody (Hu-Mikβ1) to the IL2/IL15Rβ receptor, expressed on T-LGL, is exp...

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Bibliografski detalji
Glavni autori: Steinway, Steven N, Loughran, Thomas P
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889194/
https://ncbi.nlm.nih.gov/pubmed/23634735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/eci.13.28
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