Developing an in vitro model of T cell type of large granular lymphocyte leukemia

We developed a strategy that can prolong in vitro growth of T cell type of large granular lymphocyte (T-LGL) leukemia cells. Primary CD8+ lymphocytes from T-LGL leukemia patients were stably transduced with the retroviral tax gene derived from human T cell leukemia virus type 2. Expression of Tax ov...

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Bibliographic Details
Main Authors: Ren, Tong, Yang, Jun, Broeg, Katie, Liu, Xin, Loughran, Thomas P., Cheng, Hua
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865428/
https://ncbi.nlm.nih.gov/pubmed/24183305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.10.002
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