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Dynamics of yeast histone H2A and H2B phosphorylation in response to a double-strand break
In budding yeast, a single double-strand break (DSB) triggers extensive ATM (Tel1) and ATR (Mec1)-dependent phosphorylation of histone H2A (γ-H2AX) around the DSB. We describe Mec1- and Tel1-dependent phosphorylation of γ-H2B at H2B-T129. γ-H2B formation is impaired by γ-H2AX and its binding partner...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889172/ https://ncbi.nlm.nih.gov/pubmed/24336221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2737 |
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