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Hypoxia signaling – license to metastasize

Hypoxia-inducible transcription factors (HIFs) have long been linked to malignant tumor phenotypes in various cancer types, and several downstream mediators of HIF action have been identified in metastatic carcinomas. A new study links hypoxia-induced collagen remodeling to sarcoma progression, prov...

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Bibliographic Details
Main Authors: Vanharanta, Sakari, Massagué, Joan
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889127/
https://ncbi.nlm.nih.gov/pubmed/24124230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0481
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