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Metastatic competence can emerge with selection of pre-existing oncogenic alleles without a need of new mutations
Several experimental models faithfully recapitulate many important facets of human metastatic disease. Here we have performed whole exome sequencing in five widely used experimental metastasis models that were independently derived through in vivo selection from heterogeneous human cancer cell lines...
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| Publicado no: | Cancer Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4573898/ https://ncbi.nlm.nih.gov/pubmed/26208905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0562 |
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